Rifampicin combined regimens for Gram-negative infections: data from the literature

Antibiotics for Gram-negative infections

We do need them, and we need them now! New antibacterial drugs have been developed on the last 2 years for Grampositive agents,(1) but not with new targets. There has been real progress in developing antimycobacterial agents, including some new modes of action;(2) however, what we have available today for Gramnegative multiresistant bacteria is the same we had 5 years ago, except for some molec...

Antimicrobial Resistance in Gram-negative Bacilli Isolated from Urinary Tracts Infections

Efficacy of Amikacin and Imipenem Against Multi-Drug Resistant Gram-Negative Bacteria Isolated From Wound Infections

Background and Objective: Gram-negative pathogens are considered the common cause of wound infections associated with increased mortality and morbidity rates. Antibiotics combination has been used to overcome this problem. Aims: In this study, we identify Gram-negative pathogens found in wound infections and assess the in-vitro efficacy of a combination of amikacin and imipenem against the resi...

Antagonistic activity of Streptomyces gresiofuscus PTCC1628 against isolated Gram negative bacteria from Urinary Tract Infections

  Antibiotics are the best known products of actinomycete. Over 5,000 antibiotics have been identified from the cultures of Gram positive and Gram-negative organisms, and filamentous fungi, but only about 100 antibiotics have commercially been used to treat human, animal and plant diseases. The genus, Streptomycete, is responsible for the formation of more than 60% of known antibiotics. Bacteri...

Emerging gram-negative enteric infections.

This is an overview describing the microbiology, epidemiology, clinical presentations, laboratory diagnosis, and treatment of emerging gram-negative enteric infections. This review illustrates the shifts in epidemiology of infections caused by new and reemerging bacteria and highlights the role of the clinical microbiology laboratory in detecting these pathogens. It concludes with suggestions f...